San Francisco was the most expensive city for business travelers for the second consecutive year, according to Business Travel News’ 2015 Corporate Travel Index. 
 
The analysis includes spend on hotel, food and cars. Following San Francisco was New York City ($494.95); Boston ($465.52); Honolulu ($398.83); and Seattle ($389.11). The overall U.S. average was $306.91.
 
San Francisco’s hotel costs also topped the list at $$338.20, followed by New York City at $305.10; Boston at $300.89; Washington, D.C., at $232.04; and Honolulu at $231.95. The U.S. average was $163.13.